China 40216-83-9 H-Hyp-Ome·HCl Wopanga ndi Fakitale |Jiayinglai

40216-83-9 H-Hyp-Ome·HCl

Kufotokozera Kwachidule:

Maonekedwe	White ufa
MF	C6H12ClNO3
MW	181.62
Chiyero	98+

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Mkhalidwe wamayendedwe
Zitha kukhala kutentha kwabwino

Limbikitsani njira yotumizira
Ndi mpweya Pamtunda Panyanja

Malo osungira:
Khalani pamalo amdima, M'mlengalenga, Kutentha kwachipinda

Alumali moyo
Pafupifupi zaka 2

Oda Yochepa Kwambiri:
1kg (kukambirana)

Chitsimikizo:COA, malo osungunuka, SpecificRotation [α]_D²⁰

Titumiza deta iliyonse yomwe mukufuna.Mutha kuwona zomwe zili kale ngati zofotokozera.

Pazinthu zosinthidwa makonda, timatumiza zatsopano zikatuluka.

Mawu ofanana ndi mawu

H-HYP-OMEHCL;
HL-HYP-OMEHCL;
HYDROXYPROLINE-OMEHCL;
(2S, 4R) -trans-4-hydroxy-L-prolinemethylesterhydrochloride;
4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDESALT;
L-4-TRANS-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE

Kupaka mkati

Nthawi zambiri amagwiritsidwa ntchito ponyamula ufa.Zimatengera makasitomala` zofunika.Chifukwa chake, tiuzeni zomwe mukufuna musanapake ngati muli ndi zopempha zapadera.

kulongedza kwakunja

1kg mpaka 25kg Kulongedza kwakunja kumakhala kovuta.Ndipo n'zovuta kudula ndi kuwononga.Ikhoza kuteteza katundu wanu mwangwiro.

Mapulogalamu

Kugwiritsa ntchito: H-Hyp-OMe·HCl imagwira ntchito ngati cholumikizira cha ADC (antibody-drug conjugate) cholumikizira cha kaphatikizidwe ka ADCs.Ma ADC, opangidwa ndi antibody ndi cytotoxin omwe amalumikizidwa kudzera pa cholumikizira cha ADC, amathandizira kutumiza ma cytotoxins kuti ayang'ane ma cell, potero kuchiza matenda enaake.Kuphatikiza apo, H-Hyp-OMe·HCl ndi PROTAC (protein degradation targeting chimera) cholumikizira chokhazikika pamaketani a alkyl, omwe amagwiritsidwa ntchito popanga ma PROTAC.Ma PROTAC, omwe ali ndi ma ligand awiri osiyana omwe amalumikizidwa ndi cholumikizira, amagwiritsa ntchito ma cell a ubiquitin-proteasome system kuti awononge mapuloteni omwe akufuna.

Katundu: H-Hyp-OMe·HCl ndi ufa wa amorphous woyera kapena wachikasu pang’ono umene umasungunuka mu zosungunulira monga madzi, methanol, ndi ethanol.Imawonetsa kukhazikika kwabwino komanso kuyanjana kwachilengedwe, kusunga ntchito zake komanso kukhazikika pansi pamikhalidwe yakuthupi.

Ponseponse, H-Hyp-OMe·HCl imakhala ndi gawo lofunikira pakuphatikizika kwa ma ADC ndi ma PROTAC monga chida chofunikira kwambiri cha biochemical ndi kupanga mankhwala.Limapereka njira zatsopano zochizira matenda.Pamene kafukufuku akupitilira komanso ukadaulo ukupita patsogolo, mwayi wogwiritsa ntchito H-Hyp-OMe·HCl ukuyembekezeka kukulirakulira.

zokhudzana ndi mankhwala

L-Hyp-OH	HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl	L-Hyp-Obzl.Hcl
Boc-L-Hyp-OH	Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome	Boc-L-Hyp-oet
Fmoc-L-Hyp-OH	Fmoc-L-Hyp(tbu)-OH
Cbz-L-Hyp-OH	Cbz-L-Hyp-OMe

Kuposa

1. Timapereka makonda zomwe mukufuna.
2. Ubwino wapamwamba & mtengo wampikisano ukhoza kuperekedwa.
3. Tikulonjezani njira yonse yotsatila kwa inu.
4. Mafunso a ogulitsa ndi zikalata zaukadaulo zitha kuperekedwa ngati atapempha mutakumana ndi ndalama zina.
5. Utumiki wabwino pambuyo pa malonda kapena chitsimikizo : Funso lanu lirilonse likhoza kuthetsedwa posachedwa.
6. Tumizani katundu wopikisana ndi kutumiza kunja kochuluka kwambiri chaka chilichonse.
7. Zitsanzo zaulere zomwe zimaperekedwa kuti ziwone khalidwe musanapereke malipiro.

Zam'mbuyo: 33208-99-0 L-Ala-NH2.HCl

Ena: 7362-93-8 H-Asp-OBzl

Lembani uthenga wanu apa ndikutumiza kwa ife