2424-92-2 EICOSANEDIOIC ACID

Organic Synthesis: EICOSANEDIOIC ACID imagwira ntchito ngati gawo lapakati pakuphatikizika kwa organic, kutenga nawo gawo pakupanga mitundu yosiyanasiyana yamagulu.Kapangidwe kake ka alkyl chain kumapangitsa kukhala chisankho choyenera kupanga mitundu ina ya mamolekyu.

Kaphatikizidwe ka Antibody-Drug Conjugates (ADCs): EICOSANEDIOIC ACID ndi cholumikizira chosaduka chomwe chimagwiritsidwa ntchito popanga ma antibody-drug conjugates (ADCs).Ma ADCs ndi mankhwala omwe amalumikiza ma antibodies ndi ma cytotoxic agents, omwe cholinga chake ndi kupereka cytotoxic wothandizila ndendende ku maselo a chotupa kudzera mu kuzindikira kwachindunji kwa ma antibodies, potero amapeza zotsatira zabwino komanso zenizeni za antitumor.

PROTAC Synthesis: EICOSANEDIOIC ACID ndi cholumikiziranso cha PROTAC kutengera unyolo wa alkyl, womwe umagwiritsidwa ntchito popanga ma PROTAC.PROTACs ndi mamolekyu omwe amagwiritsa ntchito intracellular ubiquitin-proteasome system kuti awononge mapuloteni omwe akufuna.Polumikiza minyewa iwiri yosiyana (imodzi ya E3 ubiquitin ligase ndi ina ya mapuloteni omwe mukufuna), ma PROTAC amathandizira kuwonongeka kwa mapuloteni omwe amawatsata, ndikuthandizira kwambiri pochiza matenda.