7536-55-2 Boc-L-Asn-OH

Boc-L-Asn-OH, yomwe imadziwikanso kuti BOC-L-Asparagine, ndiyochokera ku amino acid yofunikira yokhala ndi ntchito zosiyanasiyana.

Choyamba, Boc-L-Asn-OH amapeza kugwiritsidwa ntchito kofala mu biochemistry ndi kupeza mankhwala.Imagwira ntchito ngati gawo lofunikira pakuphatikizika kwa peptide, ndikupangitsa kuti pakhale unyolo wa peptide wokhala ndi zochitika zenizeni zamoyo.Chifukwa cha mankhwala ake apadera, Boc-L-Asn-OH amatha kuchitapo kanthu ndi ma amino acid kapena mankhwala ena, zomwe zimapangitsa kuti pakhale mankhwala atsopano kapena mamolekyu a bioactive omwe ali ndi ntchito zosiyana.

Kachiwiri, Boc-L-Asn-OH ilinso ndi ntchito mu biotechnology ndi biology ya mamolekyulu.Itha kukhala ngati amino acid yoteteza monomer, kuteteza magulu ogwira ntchito mu ma amino acid ena kapena unyolo wa peptide ku machitidwe osayenera a mankhwala panthawi ya kaphatikizidwe kapena kuyeretsedwa.Kuonjezera apo, Boc-L-Asn-OH ikhoza kugwiritsidwa ntchito posintha malo enieni pakupanga mapuloteni, kusintha mapangidwe ndi ntchito ya mapuloteni.

Kuphatikiza apo, potengera njira zopangira, Boc-L-Asn-OH imatha kupangidwa kudzera muzochita zinazake zamankhwala.Nthawi zambiri, amakonzedwa pogwiritsa ntchito tert-butoxycarbonyl chloride (kapena azide) ndi L-asparagine monga zida zoyambira.Zomwe acylation zimatsatiridwa ndi acidification pogwiritsa ntchito citric acid ndiyeno kuyeretsedwa ndi recrystallization.Kupanga kumeneku kumathandizira kukonzekera kwakukulu kwa Boc-L-Asn-OH, kukwaniritsa zofuna za ntchito zake zosiyanasiyana.