66638-37-7 Boc-N-Me-L-Tyr(tbu)-OH

Peptide Synthesis:
Boc-N-Me-L-Tyr(Tbu)-OH ndi amino acid otetezedwa omwe amagwiritsidwa ntchito popanga peptide synthesis (SPPS) ndi njira zina zopangira peptide.Ndi magulu onse a N-terminal ndi ma side-chain hydroxyl otetezedwa, imakhazikika pakutalikirana kwa unyolo wa peptide, kupeŵa zochitika zosafunika.
Pambuyo pakutha kwa unyolo wa peptide, magulu oteteza amatha kuchotsedwa pamikhalidwe yoyenera, kuwonetsa magulu aulere amino ndi hydroxyl, potero akupereka peptide kapena mapuloteni omwe amafunidwa.
Mapuloteni Engineering:
Muukadaulo wamapuloteni, amino acid wotetezedwa atha kugwiritsidwa ntchito posintha mapuloteni potengera malo.Pochita Boc-N-Me-L-Tyr(Tbu) -OH ndi malo enieni pa mapuloteni, zotsalira za methylated tyrosine zikhoza kuyambitsidwa, kusintha mapuloteni ndi ntchito yake.
Kapangidwe ndi Kukula kwa Mankhwala:
Methylated tyrosine imatha kuwonetsa zochitika zenizeni zamoyo kapena katundu wa pharmacokinetic pamapangidwe ena amankhwala.Pogwiritsa ntchito Boc-N-Me-L-Tyr(Tbu)-OH monga chomangira, ofufuza amatha kufufuza momwe angathere pochizira komanso mankhwala a mamolekyu a mankhwala omwe ali ndi methylated tyrosine.
Kafukufuku wa Biochemical ndi Biological:
Pakufufuza kwachilengedwe komanso kwachilengedwe, ma amino acid otetezedwawa amatha kukhala ngati chida chowerengera gawo la methylated tyrosine pakulumikizana kwa mapuloteni, kutulutsa ma sign, ntchito za enzyme, ndi zina.
Bioconjugation ndi zilembo:
Magulu a methyl ndi otetezedwa a hydroxyl a Boc-N-Me-L-Tyr(Tbu)-OH amapanga chisankho choyenera cha bioconjugation ndi ma label reaction.Pochotsa magulu oteteza ndikuchitapo kanthu ndi mamolekyu ena kapena zinthu zogwira ntchito ndi biologically, mamolekyu olembedwa omwe ali ndi zochitika zapadera zamoyo akhoza kukonzedwa.