200937-17-3 Boc-D-Leu-OH•H2O

Kupeza kwa Biochemistry ndi Mankhwala:
Monga chochokera ku amino acid, Boc-D-Leu-OH·H2O imagwira ntchito yofunika kwambiri popanga ma peptide ndi mapuloteni omwe amakhala ndi biologically.Kusintha kwa mankhwala a pawiriwa kungayambitse chitukuko cha mankhwala atsopano kapena ofuna mankhwala ochizira matenda osiyanasiyana.Makhalidwe apadera a D-leucine angapereke zochitika zenizeni zamoyo ku ma peptides opangidwa kapena mapuloteni.
Peptide Synthesis:
Mu kaphatikizidwe ka peptide yolimba, Boc-D-Leu-OH · H2O ndi amino acid monomer.Gulu lake loteteza la N-terminal Boc limalola amino acid ligation ndi chitetezo pansi pamikhalidwe yofatsa, zomwe zimapangitsa kuphatikizika kwa maunyolo a peptide ndi machitidwe ndi ntchito zake.
Kafukufuku wa Laboratory:
Boc-D-Leu-OH · H2O amagwiritsidwa ntchito kwambiri popanga peptide ndi maphunziro a protein.Mwa kuphatikiza ndi ma monomers ena amino acid, ma peptide osiyanasiyana amatha kupangidwa kuti afufuze momwe mapuloteni-mapuloteni ndi mapuloteni-ligand amagwirira ntchito, komanso momwe mapuloteni amagwirira ntchito komanso njira zoyendetsera.
Peptide Reagents ndi Synthetic Auxiliaries:
Boc-D-Leu-OH · H2O ikhoza kukhala ngati choteteza kapena condensing agent mu kaphatikizidwe ka peptide, kuwongolera magwiridwe antchito ndi chiyero cha kaphatikizidwe ka peptide.Kuphatikiza apo, itha kugwiritsidwa ntchito ngati peptide reagent polemba peptide, kusintha, ndi kuzindikira.
Asymmetric Synthesis:
Chifukwa cha chikhalidwe cha chiral cha D-leucine, Boc-D-Leu-OH · H2O ali ndi mwayi wogwiritsa ntchito mu asymmetric synthesis.Pophatikiza ndi mamolekyu ena a chiral, ma peptides ndi mapuloteni okhala ndi ma stereoconfigurations enieni amatha kupangidwa kuti aphunzire momwe chirality imakhudzira zochitika zamoyo.