103898-11-9 Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate

Kupezeka kwa Mankhwala: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate imagwiritsidwa ntchito ngati gulu loteteza potulukira mankhwala.Imakhudzidwa ndi magulu ogwira ntchito monga ma hydroxyls ndi ma amines mu mamolekyu a mankhwala, kupanga zotumphukira zotetezedwa za tert-butoxycarbonyl (Boc).Chitetezochi chimalola kukhazikika kokhazikika komanso kuyeretsedwa, ndipo gulu la Boc litha kuchotsedwa pansi pamikhalidwe yabwino kuti liwonetse gulu loyambirira lomwe limagwira ntchito kuti lizitsatiranso zina kapena maphunziro achilengedwe.Chifukwa chake, ili ndi mwayi wogwiritsa ntchito kaphatikizidwe ka mankhwala, kusintha kwa mankhwala, komanso kutulutsidwa kwa mankhwala olamulidwa.

Kaphatikizidwe ka Peptide: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate imapezanso kugwiritsidwa ntchito ngati cholumikizira mu kaphatikizidwe ka peptide.Imatha kuchitapo kanthu ndi gulu la carboxyl la ma amino acid, kupanga zomangira zokhazikika za amide kuti zilumikize ma amino acid awiri kapena kupitilira apo, ndikupanga maunyolo a peptide okhala ndi mindandanda ndi mapangidwe ake.Cholumikizirachi chimagwiritsidwa ntchito kwambiri popanga peptide yolimba, kaphatikizidwe ka peptide yamadzimadzi, ndi njira zina.

Kafukufuku wa Zamoyo Zamoyo: Chifukwa cha chilengedwe chake chosawonongeka, Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate imagwiritsidwanso ntchito ngati chida pakufufuza kwa biochemical.Mwachitsanzo, angagwiritsidwe ntchito ngati cholumikizira mu kaphatikizidwe wa antibody-drug conjugates (ADCs), kulumikiza mankhwala ndi ma antibodies kuti aperekedwe ndi kumasulidwa.Kuonjezera apo, angagwiritsidwe ntchito pophunzira kuyanjana kwa mapuloteni-mapuloteni ndi mapuloteni-ligand, komanso momwe mapuloteni amapangidwira ndikugwira ntchito mkati mwa maselo.